Lepton focuses on subtle and precise silencing of coding RNA expression by small non-coding RNA molecules, working via the DROSHA/DICER/RISC pathways, small interfering RNA (siRNA), and microRNA (miRNA), to develop products and services to, ultimately, improve therapies for underserved diseases and improve and change patients' lives. For additional information please visit About Lepton Pharmaceuticals Find and apply for the latest jobs near Lepton from Knott Mill, Manchester Airport to. Non-exclusive licenses are available for research and sale of products and services across multiple fields including: research tools, kits, reagents discovery of novel targets for therapeutic intervention cell lines for discovery and screening of novel drug candidates GMP production of healthcare products companion animal and livestock health production of industrial materials such as enzymes, biofuels and chemicals and synthetic biology. The company was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property held by Dr.
This technology aims to revolutionize the immune cell cancer therapy field.įinancial details of the agreement are not disclosed.ĮRS Genomics is a biotechnology company based in Dublin, Ireland. The Castling technology allows, in a single gene editing event in the immune cell (either allogeneic or autologous), to impact the expression of a multitude of genes in the immune cells, once such miRNAs penetrate the microenvironment of cancer cells. (Dimtel), San Jose, CA, USA 52 Dipartimento di Ingegneria. miRNAs are noncoding RNAs that each affects the expression of hundreds of coding genes. This study covers a highest-luminosity high-energy lepton collider. The Castling technology is a proprietary, miRNA-based general technology platform, essentially consisting of the manipulation of miRNA expression to achieve enhanced efficacy and longevity (reduced exhaustion) of cell-based therapies.
It will greatly assist us to develop our innovative Castling technology to significantly improve immune cells efficiency and longevity to fight cancer."Įric Rhodes, CEO at ERS Genomics added: "Lepton's Castling technology has great potential to impact the field of immunotherapies and we are pleased to help enable Lepton in pursuing this exciting approach."
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Daniel Zurr, CEO of Lepton said: "We are very pleased to establish this relationship and license agreement with ERS Genomics. Lepton Pharmaceutical LTD is a biotechnology company developing a proprietary, breakthrough technology (Castling Technology) to substantially improve adaptive cell-mediated immune response (T-cells, CAR-T-cells, NK-cells.)ĭr.
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